Links







EPITALON Studies



More than 100 studies of Epitalon Click here

Experimental research on ageing in Russia. Click here

Peptide regulation of ageing. Click here

Geroprotective effect of thymalin and epithalamin. Click here

Study of the anti-tumor effect of polypeptide pineal extract // Oncology. - 1979. Click here

Increase in lifespan of rats following polypeptide pineal extract treatment // Exp. Pathol. - 1979. Click here

Effect of low-molecular-weight factors of thymus, pineal gland and anterior hypothalamus on immunity, tumor incidence and lifespan of C3H/Sn mice // Mech.Ageing Dev. - 1982. Click here

Effect of low-molecular-weight factors of thymus and pineal gland on lifespan and spontaneous tumour development in female mice of different age // Mech. Ageing Dev. - 1989. Click here

The pineal peptides: interaction with indoles and the role in aging and cancer // Neuro-endocrinology: New Frontiers. Click here

Effect of pineal peptide preparation (epithalamin) on lifespan and pineal and serum melatonin level in old rats // Ann. N.Y. Acad. Sci. - 1992. Click here

Bioactive peptides from bovine pineal gland and bone marrow extracts. In: «Chemistry of Peptides and Proteins» DWI Report: Aachen. - 1993. Twenty years of study on effect of pineal peptide preparation: epithalamin in experimental gerontology and oncology // Ann. N.Y. Acad. Sci. - 1994. Click here

Approach to the prophylaxis and treatment of age-related pathology // Romanian J. of Gerontology and Geriatrics. – 1998.

Claude Bernard was right: hormones may be produced by “non-endocrine” cells // Neuroendocrinology Lett. – 2000. Click here

US Patent N 6,727,227 B1 «Tetrapeptide revealing geroprotective effect, pharmacological substance on its basis, and the method of its application»; 27.04.2004.

Inhibitory effect of the peptide epitalon on the development of spontaneous mammary tumors in Her-2/NEU transgenic mice // Int. J. Cancer. – 2002. V. 101. - P. 7-10. Free here : Click here

Spontaneous mutagenesis, carcinogenesis and aging in SAM mice: effect of melatonin, epitalon and neuronal // Proceedings of the 19th SAM meeting. – Ed. T.Takeda. Kyoto. - 2004.

Epitalon peptide induces telomerase activity and telomere elongation in human somatic cells. // Bulletin Exp. Biol. Med. (Rus). – 2004. Click here

Peptide promotes overcoming of the division limit in human somatic cell // Bulletin Exp. Biol. Med. (Rus). – 2004. Click here

Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice. Nature. 2011. Click here

Wiki on thymus Click here

Wiki on pineal gland Click here

Wiki on Hayflick limit Click here


 
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